周禮君 教授  Chau, Lai-Kwan                               Professor

Date of employment: Aug. 1, 1995

Specialty: Analytical Chemistry, Materials Chemistry

TEL (O): (886-5) 272-0411
ext.
66411

Email: chelkc@ccu.edu.tw

Lab Webpage

 

到校日期:8481

專長領域:分析化學、材料化學

 

聯絡電話:(05)272-0411 ext. 66411

電子信箱:chelkc@ccu.edu.tw

研究室:Rm 414

實驗室網頁

 

 

B.S.in Chemistry, Chinese University of Hong Kong, 1980

M.S. in Chemistry, University of Houston, 1986

Ph.D. in Iowa State University, 1990

Assistant Research Scientist, Department of Chemistry, University of Arizona, 1990-1994

Senior Fellow, Center for Bioengineering, University of Washington, 1994-1995

Assoc. Professor, National Chung Cheng University, 1995-2003

Professor, National Chung Cheng University, 2003-

Chairperson, Department of Chemistry and Biochemistry, National Chung Cheng University (2011-12)

Dean, College of Science, National Chung Cheng University(2012-)

 

學士 香港中文大學化學系理學士 (1980)

碩士 美國休士頓大學化學碩士 (1986)

博士 美國愛俄華州立大學分析化學博士 (1990)

美國亞里桑那大學化學系助理研究員(1990-1994)

美國華盛頓大學生物工程中心資深研究員(1994-1995)

國立中正大學化學系副教授 (1995-2002)

國立中正大學化生系副教授 (2002-2003)

國立中正大學化生系教授 (2003-)

國立中正大學化學暨生物化學系系主任(2011-2012)

國立中正大學理學院院長(2012-)

Research Interests

Optical waveguide-based particle plasmon resonance biosensing

Raman-barcoded bead sensors

Sol-gel, nanoparticle, and molecular films

 

研究重點

光波導式粒子電漿共振生物感測器

拉曼編碼感測珠

溶膠-凝膠、奈米粒子及分子膜

Selected Publications 代表著作
  • Wu, C.-W.; Chiang, C.-T.; Chen, C.-H.; Chiang, C.-S.; Wang, C.-T.; Chau, L.-K.* “Self-referencing fiber optic particle plasmon resonance sensing system for real-time biological monitoring.” Talanta 2016, 146, 291-198.

  • Lyu, S.-R.*; Chiang, C.-Y.; Cherng, J.-Y.; Huang, Y.-C.; Li, C.-H.; Lin, Y.-J.; Chang, C.-M.; Chau, L.-K.* “Role of medial abrasion phenomenon in the pathogenesis of knee osteoarthritis.” Med. Hypotheses 2015, 85, 207-211.

  • Ku, Y.-F.; Li, H-Y.; Hsieh, W.-H.; Chau, L.-K.; Chang, G.-E.* “Enhanced sensitivity in injection-molded guided-mode-resonance sensors via low-index cavity layers.”  Opt. Express 2015, 23, 14850-14859.

  • Li, H.-Y.; Hsu, W.-C.; Liu, K.-C.; Chen, Y.-L.; Chau, L.-K.; Hsieh, S.; Hsieh, W.-H.* “A low cost, label-free biosensor based on a novel double-sided grating waveguide coupler with sub-surface cavities.”  Sens. Actuat. B 2015, 206, 371-380.

  • Lin, H.-Y.; Huang, C.-H.; Hsieh, Liu, L.-H.; W.-H.; Lin, Y.-C.; Chu, C.-C.; Wang, S.-T.; Kuo, I-T.; Chau, L.-K.*; Yang, C.-Y.* “On-line SERS detection of single bacterium using novel SERS nanoprobes and a microfluidic dielectrophoresis device.”  Small 2014, 10, 4700-4710.

  • Chen, W.-H.; Tseng, Y.-T.; Hsieh, S.; Liu, W.-C.; Hsieh, C.-W.; Wu, C.-W.;  Huang, C.-H.; Lin, H.-Y.; Chen, C.-W.; Lin, P.-Y.; Chau, L.-K.* “Silanization of solid surfaces via mercaptopropylsilatrane: a new approach of  constructing gold colloid monolayers.”  RSC Adv. 2014, 4, 46527-46535.

  • Hsieh, M.-L.; Chau, L.-K.*; Hon, Y.-S. “Single-step approach for fabrication of vancomycin-bonded silica monolith as chiral stationary phase.”  J. Chromatogr. A 2014, 1358, 208-216.

  • Lin, H.-Y.; Huang, C.-H.; Lu, S.-H.; Kuo, I-T.; Chau, L.-K. “Direct detection of orchid viruses using nanorod-based fiber optical particle plasmon resonance immunosensor” Biosens. Bioelectron. 2014, 51, 371-378.

  • Hsu, W.-T.; Feng, G.-H.; Cho, C.-L.; Chau, L.-K. “Nonspecific binding removal and specific binding regeneration using longitudinal acoustic waves” RSC Adv. 2013, 3, 16159-16166.

  • Huang, Y.-C.; Chiang, C.-Y.; Li, C.-H.; Chang, T.-C.; Chiang, C.-T.; Chau, L.-K.; Huang, K.-W.; Wu, C.-W.; Wang, S.-C.; Lyu, S.-R. “Quantification of tumor necrosis factor-a and matrix metalloproteinases-3 in synovial fluid by a fiber-optic particle plasmon resonance sensor” Analyst 2013, 138, 4599-4606.

  • Li, H.-Y.; Huang, C.-H.; Chen, S.-H.; Liu, Y.-C.; Chang, W.-Z.; Chau, L.-K. “Tubular waveguide evanescent field absorption biosensor based on particle plasmon resonance for multiplex label-free detection” Biosens. Bioelectron. 2013, 41, 268-274.

  • Chang, T.-C.; Wu, C.-C.; Wang, S.-C.; Chau, L.-K.; Hsieh, W.-T. “Using a fiber optic particle plasmon resonance biosensor to determine kinetic constants of antigen-antibody binding reaction” Anal. Chem. 2013, 85, 245-250.

  • Chau, L.-K., Chang, H.-T., Eds., “From Bioimaging to Biosensors - Noble Metal Nanoparticles in Biodetection”, Pan Stanford Publishing, Singapore, 2013.  [ISBN: 978-981-4267-24-3 (Hardback), 978-981-4303-10-1 (eBook)]

  • 林幸瑩、黃貞翰、周禮君 新型光學奈米探針:表面增強拉曼光譜標籤於生物檢測分析與應用化學 2013, 71, 243-252.

  • Lin, H.-Y.; Huang, C.-H.; Huang, C.-C.; Liu, Y.-C.; Chau, L.-K. “Multiple resonance fiber-optic sensor with time division multiplexing for multianalyte detection” Opt. Lett. 2012, 37, 3969-3971.

  • Tuyen, L.D.; Liu, A.-C.; Huang, C.-C.; Tsai, P.-C.; Lin, J.-H.; Wu, C.-W.; Chau, L.-K.; Yang, T.S.; Minh, L.Q.; Kan, H.-C.; Hsu, C.-C. “Doubly resonant surface-enhanced Raman scattering on gold nanorod decorated inverse opal photonic crystals” Opt. Express 2012, 20, 29266-29275.

  • Tang, J.-L.; Chen, C.-H.; Chang, T.-C.; Wang, S.-C.; Chau, L.-K.; Wu, W.-T. “Fabrication and characterization of a fused silica-base optical waveguide with femtosecond fiber laser pulses” Microsyst. Technol. 2012, 18, 1815-1821.

  • Tay, L.-L.*; Huang, P.-J.; Jamshid, T.; Shannon, R.; Wu, X.-H.; John, H.; Chau, L.-K.* “Silica encapsulated SERS nanoprobe conjugated to the bacteriophage tailspike protein for targeted detection of Salmonella” Chem. Commun. 2012, 48, 1024-1026.

  • Lin, H.-Y.; Huang, C.-H.; Chau, L.-K.* “Fiber optic particle plasmon resonance sensor based on plasmonic light scattering interrogation” Ann. Phys. 2012, 524, 705-712.

  • Huang, K.-W.; Hsieh, C.-W.; Kan, H.-C.; Hsieh, M.-L.; Hsieh, S.*; Chau, L.-K.*; Cheng, T.-E.; Lin,W.-T. “Improved performance of aminopropylsilatrane over aminopropyltriethoxysilane as a linker for nanoparticle-based plasmon resonance sensor” Sens. Actuat. B 2012, 163, 207-215.

  • Huang, C.-C.; Huang, C.-H.; Kuo, I-T.; Chau, L.-K.*; Yang, T.-S.* “Synthesis of silica-coated gold nanorod as Raman tags by modulating cetyltrimethylammonium bromide concentration” Colloids Surf. A 2012, 409, 61-68.

  • Li, H.-Y.; Chen, C.-W.; Yang, H.-C.; Chau, L.-K.; Hsieh, W.-H.* “Low cost, rapid fabrication of durable molds of grating arrays for nanoimprint lithography” Microelectron. Eng. 2011, 88, 3062-3066.

  • Chen, C.-H.; Weng, T.-Z.; Wang, J.-N.; Cheng, C.-W.; Tang, J.-L.*; Chau, L.-K.*; Wu, W.-T.* “Novel multiphase D-shaped fiber optic sensor realized by femtosecond laser machining” J. Laser Micro/Nanoeng. 2011, 6, 82-86.

  • Chau, L.-K.*; Kuo, C.-W.; Chu, Y.-W.; Liao, S.-H.; Lin, Y. -T.; Wang, C. R. C.* “A fiber optic particle plasmon resonance biosensing platform based on detection of light scattering intensity from the proximal end” J. Chin. Chem. Soc. 2011, 58, 786-792.

  • Hsu, W.-T.; Hsieh, W.-H.; Cheng, S.-F.; Jen, C.-P.; Wu, C.-C.; Li, C.H.; Lee, C.-Y ; Li, W.-Y.; Chiang, C.-Y.; Lyu, S.-R.; Chau, L.-K.* “Integration of fiber optic-particle plasmon resonance biosensor with microfluidic chip” Anal.Chim. Acta 2011, 697, 75-82.

  • 周禮君 “新一代生物感測器專題報導簡介” 化學 2011, 69,191-192.

  • 陳建興、吳瑋特、湯兆崙、周禮君 “飛秒雷射精微加工系統製作光纖感測器” 科儀新知 2011, 32, 53-60.

  • Chen, H.-C.; Tsao, T.-C.; Li, W.-Y.; Shen, W.-C.; Cheng, C.-W.; Tang, J.-L.; Jen, C.-P.; Chau, L.-K.; Wu, W.-T.* “Novel U-shape gold nanoparticles-modified optical fiber for localized plasmon resonance chemical sensing” Microsyst. Technol. 2010, 16, 1207-1214.

  • Chiang, C.-Y.; Hsieh, M.-L.; Huang, K.-W. ; Chau, L.-K.*; Chang, C.-M.; Lyu, S.-R.* “Fiber-optic particle plasmon resonance sensor for detection of interleukin-1b in synovial fluids” Biosens. Bioelectron. 2010, 26, 1036-1042.

  • Chen, C.-H.; Chao, T.-C.; Li, W.-Y.; Shen, W.-C.; Cheng, C.-W.; Tang, J.-L. ; Chau, L.-K.*; Wu, W.-T.* “Novel D-type fiber optic localized plasmon resonance sensor realized by femtosecond laser engraving” J. Laser Micro/Nanoeng. 2010, 5, 1-5.

  • Chuang, Y.; Lee, C.-Y.; Lu, S.-H.; Wang, S.-C.*; Chau, L.-K.*; Hsieh, W.-H. “Using ac-field-induced electro-osmosis to accelerate biomolecular binding in fiber-optic sensing chips with microstructures” Anal. Chem. 2010, 82, 1123-1127.

  • 謝銘隆、周禮君 “貴金屬奈米粒子定域化表面電漿共振波在生物感測的應用” 化學 2010, 68, 21-32.

  • 章嘉明、周禮君 “光纖式奈米生物感測儀” 量測資訊 2010, 133, 42-45.

  • 章嘉明、李佳瑜、江昌獄、周禮君 “免標定生物感測器” 科儀新知 2010, 31, 48-55.

  • 章嘉明、李佳瑜、黃玶吉、王少君、周禮君 “貴金屬奈米粒子在生醫檢測上的應用實例” 台灣奈米會刊 2010,21, 44-50.

  • 林建宏、黃家琪、杜名碧、巫晟逸、楊子萱、周禮君、張天立、林宏彝、甘宏志、許佳振 “結合飛秒雷射直寫技術與化學修飾方法製作三維表面增強拉曼散射基板” 物理雙月刊 2010, 32, 203-207.

  • Huang, C.-T.; Jen, C.-P.*; Chao, T.-C.; Wu, W.-T.; Li, W.-Y.; Chau, L.-K. “A novel design of grooved fibers for fiber-optic localized plasmon resonance biosensors” Sensors 2009, 9, 6456-6470.

  • Wu, C.-Y.; Huang, C.-C.; Jhang, J.-S.; Liu, A.-C.; Chiang, C.-C.; Hsieh, M.-L.; Huang, P.-J.; Tuyen, L. -D.; Minh, L.-Q.; Yang, T.-S.; Chau, L.-K.; Kan, H.-C.*; Hsu, C.-C.* “Hybrid surface-enhanced Raman scattering substrate from gold nanoparticle and photonic crystal: maneuverability and uniformity of Raman spectra” Opt. Express 2009, 17, 21522-21529.

  • Huang, P.-J.; Tay, L.-L.*; Jamshid, T.; Shannon, R.; Chau, L.-K.* “Single-domain antibody-conjugated nanoaggregate-embedded beads for targeted detection of pathogenic bacteria” Chem. Eur. J. 2009, 15, 9330-9334.

  • Huang, P.-J. ; Chau, L.-K.*; Yang,T.-S.*; Tay, L.-L.; Lin, T.-T. “Nanoaggregate-embedded beads as novel Raman labels for biodetection” Adv. Funct. Mater. 2009, 19, 242–248.

  • Hsieh M.-L.; Li, G.-Y.; Chau, L.-K.*; Hon, Y.-S. “Single-step approach to b-cyclodextrin-bonded silica as monolithic stationary phases for CEC” J. Sep. Sci. 2008, 31, 1819-1827.

  • Chang, C.-Y.; Chau, L.-K.*; Hu, W.-P.; Wang, C.-Y.; Liao, J.-H. “Nickel hexacyanoferrate multilayers on functionalized mesoporous silica supports for selective sorption and sensing of cesium” Microporous Mesoporous Mater. 2008, 109, 505–512.

  • Wang, S.-C.*; Chen, H.-P.; Lai, Y.-W.; Chau, L.-K.; Chuang, Y.-C.; Chen, Y.-J. “Using nonlinear ac electrokinetics vortex flow to enhance catalytic activities of sol-gel encapsulated trypsin in microfluidic devices” Biomicrofluidics 2007, 1, 034104.

  • Lai, N.-S.; Wang, C.-C.; Chiang, H.-L.; Chau, L.-K.* “Detection of antinuclear antibodies by a colloidal gold modified optical fiber: comparison with ELISA” Anal. Bioanal. Chem. 2007, 388, 901-907.

  • Lin, C.-L.; Shih, C.-L.; Chau, L.-K.* “Amperometric L-lactate sensor based on sol-gel processing of an enzyme-linked silicon alkoxide” Anal. Chem. 2007, 79, 3757-3763.

  • Chen, C.-D.; Cheng, S.-F. ; Chau, L.-K.*; Wang, C. R. C.* “Sensing capability of the localized surface plasmon resonance of gold nanorods” Biosens. Bioelectron. 2007, 22, 926-932.

  • Lin, T.-A.; Li, G.-Y.; Chau, L.-K.* “Sol-gel monolithic anion-exchange column for capillary electrochromatography” Anal. Chim. Acta. 2006, 576, 117-123.

  • Tang, J.-L.*; Cheng, S.-F.; Hsu, W.-T.; Chiang, T.-Y.; Chau, L.-K.* “Fiber-optic biochemical sensing with a colloidal gold-modified long period fiber grating” Sens. Actuat. B 2006, 119, 105-109.

  • Chau, L.-K.*; Lin, Y.-F.; Cheng, S.-F.; Lin, T.-J.* “Fiber-optic chemical and biochemical probes based on localized surface plasmon resonance” Sens. Actuat. B 2006, 113, 100-105.

  • 侯鎮球、許偉庭、周禮君 “高中職奈米材料課程實驗之設計—利用化學與電化學還原法製備銀奈米粒子” 化學  2006, 64, 305-312.

  • 許偉庭、周禮君 “貴金屬奈米粒子感測器” 科儀新知 2006, 28, 38-45.

  • Cheng, S.-F.; Pao, K.-C.; Chau, L.-K.* “Sol-gel-coated poly(methyl methacrylate) as a substrate for localized surface plasmon resonance biosensors” J. Biomed. Nanotechnol. 2005, 1, 143-150.

  • 許智偉、鄭淑芳、周禮君 “光子晶體之製備及其於化學感測上的應用” 化學 2005, 63, 431-442.

  • Lin, C.-L.; Tien, P.; Chau, L.-K.* “Electrochemical behavior of an anion-exchanger modified electrode prepared by sol-gel processing of an organofunctional silicon alkoxide” Electrochim. Acta 2004, 49, 573-580.

  • Cheng, S.-F.; Chau, L.-K.* “Colloidal gold modified optical fiber for chemical and biochemical Sensing” Anal. Chem. 2003, 75, 16-21.

  • 周禮君、林明祥、謝嘉育、余俊慶 “奈米結構含鈦氧化物光電催化材料與環境及能源” 光訊 2002, 95, 9-12.

  • 蔡裕榮、周禮君 “以溶膠凝膠法製備透明導電氧化物薄膜的探討” 化學  2002, 60, 307-318.

  • Lin, C.-C.; Chau, L.-K.*; Chang, S.-S.; Wang, C. R. C.* “Langmuir-Blodgett films of alkanethiolate gold nanorods” J. Chin. Chem. Soc. 2003, 50, 1015-1021.

  • Hsieh, Y.-Y.; Lin, Y.-H.; Yang, J.-S.; Wei, G.-T.*; Tien, P.; Chau, L.-K.* “Electroosmotic flow controllable coating on capillary surface by sol-gel process for capillary electrophoresis” J. Chromatogr. A 2002, 952, 255-266.

  • Li, C.-I; Lin, Y.-H.; Shih, C.-L.; Tsaur, J.-P.; Chau, L.-K.* “Sol-gel encapsulation of lactate dehydrogenase for optical sensing of L-lactate” Biosens. Bioelectron. 2002, 17, 323-330.

  • Yeh, T.-C.; Tien, P.; Chau, L.-K.* “Fiber-optic evanescent-wave absorption copper(II) sensor based on sol-gel-derived organofunctionalized silica cladding” Appl. Spectrosc. 2001, 55, 1320-1326.

  • Tien, P.; Chau, L.-K.*; Hsieh, Y.-Y.; Lin, W.-C.; Wei, G.-T.* “Anion-exchange material with pH-switchable surface charge prepared by sol-gel processing of an organofunctional silicon alkoxide”, Chem. Mater. 2001, 13, 1124-1130.

  • Tseng, J.-Y.; Lin, M.-H.; Chau, L.-K.* “Preparation of colloidal gold multilayers with  3-(mercaptopropyl)trimethoxysilane as a linker molecule” Colloids Surf. A 2001, 182, 239-224.

  • 周禮君、田珮 “有機無機混成溶凝膠及其應用” 強化塑膠廣用新知 2001, 86, 24-35.

  • Wang, C.-C.; Li, C.-I; Lin, Y.-H.; Chau, L.-K.* “Detection of riboflavin based on fluorescence enhancement of evanescent-wave excited β-cyclodextrin complex in sol-gel-derived porous coatings” Appl. Spectrosc. 2000,54, 15-19.

  • 周禮君、田珮 “有機矽烷氧基前驅物衍生的有機無機混成溶凝膠材料” 化工技術 2000, 8, 152-164.

  • Tien, P.; Chau, L.-K.*Novel sol-gel-derived material for separation and optical sensing of metal ions: propyl-ethylenediamine triacetate functionalized silica” Chem. Mater. 1999, 11, 2141-2147.

  • Chau, L.-K.*; Osborn, T.; Wu, C.-C.; Yager, P.* “Microfabricated silicon flow cell for optical monitoring of biological fluids” Anal. Sci. 1999, 15, 721-724.