林群欽 助理教授 Lin, Eugene C.                Assistant Professor

Date of employment: Aug. 1, 2018

Specialty: Magnetic resonance spectroscopy and imaging, Physical chemistry, and Biophysics

TEL (O): (886-5) 272-0411
ext.
664
18

Email:cheel@ccu.edu.tw

Lab Webpage

 

到校日期:107年81

專長領域: 核磁共振光譜影像、物理化學、生物物理

聯絡電話:05-2720411 ext. 66418

電子信箱:cheel@ccu.edu.tw

研究室:Rm 404

實驗室網頁

B.S. in Applied Chemistry, National Chi Nan University, 2006

M.S. in Chemistry, National Chung Hsing University, 2008

Ph.D in Chemistry and Biochemistry, University of California, San Diego, 2015

Postdoc Fellow, Vanderbilt University Institute of Imaging Science, 2015-2018

Assistant Professor, National Chung Cheng University, 2018-

學士 國立暨南國際大學應用化學系學士 (2006)

碩士 國立中興大學化學系碩士 (2008)

博士 美國加州大學聖地牙哥分校化學暨生物化學系博士 (2015)

美國范德堡大學影像科學中心博士後研究 (2015-2018)

國立中正大學化生系助理教授 (2018-)

 

 

Research Interests

Developing techniques of magnetic resonance spectroscopy and imaging

Studying membrane proteins with NMR

Diagnosis diseases with CEST (chemical exchange saturation transfer) MRI

Applications of biological and medical imaging 

研究重點

開發核磁共振光譜影像技術

以核磁共振光譜研究膜蛋白

以化學交換飽和核轉移磁共振影像診斷疾病

生物醫學影像應用

Selected Publications 代表著作
  • Zhang, C.; Idelbayev, Y.; Tao, Y.; Duggan, B. M.; Lin, E. C.; Gerwick, E. C.; Cottrell, G. W.; Gerwick, W. H. “Small Molecule Accurate Recognition Technology (SMART) to Enhance Natural Products Research.” Sci. Rep. 2017, 7, 14243.

  • Webb, J. A.; Ou, Y.-C.; Faley, S.; Hittinger, J.; Cutright, C. C.; Lin, E. C.; Bellan, L. M.; Bardhan, R. “Theranostic Gold Nanoantennas for Simultanoeus Multiplexed Raman Imaging and Photothermal Therapy.” ACS Omega 2017, 2, 3583-3594.

  • Zhang, X.-Y.; Xie, J.; Wang, F.; Lin, E. C.; Xu, J.; Gochberg, D. F.; Gore, J. C.; Zu, Z. “Assignment of the molecular origins of CEST signals at 2 ppm in rat brain.” Magn. Reson. Med. 2017, 78, 881-887.

  • Zu, Z.; Louie, E. A.; Lin, E. C.; Jiang, X.; Does, M. D.; Gore, J. C.; Gochberg, D. F. Chemical Exchange Rotation Transfer Imaging of Intermediate Exchanging Amines at 2 ppm.” NMR in Biomed. 2017, 30, e3756.

  • Zhang, H.; Lin, E. C.; Das, B. B.; Tian, Y.; Opella, S. J. “Structural determination of virus protein U from HIV-1 by NMR in membrane environments.” BBA-BIOMEMBRANES 2015, 1848, 3007-3018.

  • Lin, E. C.; Opella, S. J. “Covariance Spectroscopy in High-Resolution Multi-dimensional Solid-state NMR.” J. Magn. Reson. 2014, 239, 57-60.

  • Lin, E. C.; Opella, S. J. “Sampling Scheme and Compressed Sensing Applied to Solid-State NMR Spectroscopy.” J. Magn. Reson. 2013, 237, 40-48.

  • Das, B. B.; Lin, E. C.; Opella, S. J. “Experiments Optimized for Magic Angle Spinning and Oriented Sample Solid-State NMR of Proteins.” J. Phys. Chem. B 2013, 117, 12422-12431.

  • Hsu, C.-C.; White, N. M.; Hayashi, M.; Lin, E. C.; Poon, T.; Banerjee, I.; Chen, J.; Pfaff, S. L.; Macagno, E. R.; Dorrestein, P. C. “Microscopy ambient ionization top-down mass spectrometry reveals developmental patterning.Proc. Natl. Acad. Sci. U. S. A. 2013, 110, 14855-14860.

  • Chien, M.-P.; Thompson, M. P.; Lin, E. C.; Gianneschi, N. C. “Fluorogenic Enzyme-Responsive Micellar Nanoparticles.” Chem. Sci. 2012, 3, 2690-2694.

  • Lin, E. C.; Opella, S. J. “1H assisted 13C/15N heteronuclear correlation spectroscopy in oriented sample solid-state NMR of single crystal and magnetically aligned samples.” J. Magn. Reson. 2011, 211, 37-44.

  • Lin, E. C.; Wu, C. H.; Yang, Y.; Grant, C. V.; Opella, S. J. “1H-13C separated local field spectroscopy of uniformly 13C labeled peptides and proteins.” J. Magn. Reson. 2010, 206, 105-111.

  • Tang, H.-Y.; Lin, C.-C.; Wang, L.-S.; Yang, W.-C.; Liao, K.-H.; Li, F.-Y.; Liao, M. Y. “Quantum size effect on 67Zn-NMR measurements of ZnS nanoparticles.” Phys. Rev. B 2008, 77, 165420-165425.